Masashi Yukawa, Yusuke Yamada and Takashi Toda
Suppressor analysis uncovers that MAPs and microtubule dynamics balance with the Cut7/Kinesin-5 motor for mitotic spindle assembly in Schizosaccharomyces pombe
Masashi Yukawa, Tomoaki Yamauchi, Naoaki Kurisawa, Shakil Ahmed, Ken-ichi Kimura, and Takashi Toda (2018)
Fission yeast cells overproducing HSET/KIFC1 provides a useful tool for identification and evaluation of human kinesin-14 inhibitors
Fungal Genetics and Biology Volume 116, July 2018, Pages 33–41
Collopy LC, Ware TL, Goncalves T, S IK, Yang Q, Amelina H, Pinder C, Alenazi A, Moiseeva V, Pearson SR, Armstrong CA, Tomita K (2018).
LARP7 family proteins have conserved function in telomerase assembly.
Nat Commun 9, 557.
Takashi Toda and Masashi Yukawa wrote a short review article in Experimental Medicine in Japanese (実験医学).
Preferenciasm of protein phosphatase: type 2A phosphatase-B55 prefers threonine to serine
Experimental Medicine （実験医学）(2018) 36：No. 3, 402-404.
Masashi Yukawa, Yusuke Yamada, Tomoaki Yamauchi, Takashi Toda(2018)
Two spatially distinct Kinesin-14 Pkl1 and Klp2 generate collaborative inward forces against Kinesin-5 Cut7 in S. pombe
J Cell Sci 131,1-11
Tang , N-H., Fong , C-S., Masuda, H., Jourdain, I., Yukawa, M. and Toda , T. (2017)
Generation and characterisation of temperature sensitive mutants of genes encoding the fission yeast spindle pole body.
PeerJ Preprint, 5, e3377v1, doi: 110.7287/peerj.preprints.3377v1
Masashi Yukawa, Tomoki Kawakami, Masaki Okazaki, Kazunori Kume, Ngang Heok Tang and Takashi Toda (2017)
A microtubule polymerase cooperates with the Kinesin-6 motor and a microtubule crosslinker to promote bipolar spindle assembly in the absence of Kinesin-5 and Kinesin-14 in fission yeast
Molecular Biology of the Cell 28, 3647-3659.
Kume K, Hashimoto T, Suzuki M, Mizunuma M, Toda T, Hirata D. (2017)
Identification of three signaling molecules required for calcineurin-dependent monopolar growth induced by the DNA replication checkpoint in fission yeast.
pii: S0006-291X(17)31487-0. doi: 10.1016/j.bbrc.2017.07.129. [Epub ahead of print]
Matsuo, Y; Maurer, SP; Surrey, T and Toda, T (2017)
Purification and characterisation of the fission yeast Ndc80 complex
Protein Expression and Purification 135, 61-69
Hori, A and Toda, T (2017)
Regulation of centriolar satellite integrity and its physiology.
Cellular and Molecular Life Sciences 74, 213-229
Matsuo, Y, Maurer, SP, Yukawa, M, Zakian, S, Singleton, MR, Surrey, T and Toda, T
An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation.
J. Cell Sci. 2016; 129 (24): 4592-4606
Abstract (J Cell Sci online)
Nunez, I; Rodriguez Pino, M; Wiley, DJ; Das, ME; Chen, C; Goshima, T; Kume, K; Hirata, D; Toda, T and Verde, F (2016)
Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5.
Elife 5, e14216
Masuda, H and Toda, T (2016)
Synergistic role of fission yeast Alp16GCP6 and Mzt1MOZART1 in γ-tubulin complex recruitment to mitotic spindle pole bodies and spindle assembly.
Molecular Biology of the Cell 27, 1753-1763
Chmielewska, AE; Tang, NH and Toda, T (2016)
The hairpin region of Ndc80 is important for the kinetochore recruitment of Mph1/MPS1 in fission yeast.
Cell Cycle 15, 740-747
Toda, T and Ohya Y (2016)
Cell Technology（細胞工学） 35(3), 205-208
Hori, A; Barnouin, K; Snijders, AP and Toda, T (2016)
A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation.
EMBO Reports 17, 326-337
Nishi-Hori, A and Toda, T (2015)
Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly（中心小体サテライトとヒトMsd１タンパク質は中心体構築に必須である）
Experimental Medicine（実験医学） 33(18), 2994-2997
Hori, A; Morand, A; Ikebe, C; Frith, D; Snijders, AP and Toda, T (2015)
The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation.
Biochemical and Biophysical Research Communications 468, 39-45
Hori, A; Peddie, CJ; Collinson, LM and Toda, T (2015)
Centriolar satellites- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly.
Molecular Biology of the Cell 26, 2005-2019
Koyano, T; Barnouin, K; Snijders, AP; Kume, K; Hirata, D and Toda, T (2015)
Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast.
Genes to Cells 20, 1046-1058
Koyano, T; Konishi, M; Martin, SG; Ohya, Y; Hirata, D; Toda, T and Kume, K (2015)
Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast.
Molecular and Cellular Biology 35, 1533-1542
Tang, NH and Toda, T (2015)
Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.
Journal of Cell Science 128, 354-363
Tang, NH and Toda, T (2015)
MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation.
Bioessays 37, 248-256
Yukawa, M; Ikebe, C and Toda, T (2015)
The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies.
Journal of Cell Biology 209, 549-562
Hori, A; Ikebe, C; Tada, M and Toda, T (2014)
Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation.
EMBO Reports 15, 175-184
Okada, N; Toda, T; Yamamoto, M and Sato, M (2014)
CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.
Molecular Biology of the Cell 25, 1969-1982
Tang, NH; Okada, N; Fong, CS; Arai, K; Sato, M and Toda, T (2014)
Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast.
FEBS Letters 588, 2814-2821
Jourdain, I; Brzeziń, EA and Toda, T (2013)
Fission yeast Nod1 is a component of cortical nodes involved in cell size control and division site placement.
PLOS ONE 8, e54142
Kakui, Y; Sato, M; Okada, N; Toda, T and Yamamoto, M (2013)
Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.
Nature Cell Biology 15, 786-796
Kume, K; Kubota, S; Koyano, T; Kanai, M; Mizunuma, M; Toda, T and Hirata, D (2013)
Fission yeast leucine-rich repeat protein Lrp1 is essential for cell morphogenesis as a component of the morphogenesis Orb6 network (MOR).
Bioscience, Biotechnology, and Biochemistry 77, 1086-1091
Masuda, H; Mori, R; Yukawa, M and Toda, T (2013)
Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly.
Molecular Biology of the Cell 24, 2894-2906
Matsuo, Y; Nishino, K; Mizuno, K; Akihiro, T; Toda, T; Matsuo, Y; Kaino, T and Kawamukai, M (2013)
Polypeptone induces dramatic cell lysis in ura4 deletion mutants of fission yeast.
PLOS ONE 8, e59887
Mori, R and Toda, T (2013)
The dual role of fission yeast Tbc1/cofactor C orchestrates microtubule homeostasis in tubulin folding and acts as a GAP for GTPase Alp41/Arl2.
Molecular Biology of the Cell 24, 1713-1724
Roseaulin, LC; Noguchi, C; Martinez, E; Ziegler, MA; Toda, T and Noguchi, E (2013)
Coordinated degradation of replisome components ensures genome stability upon replication stress in the absence of the replication fork protection complex.
PLOS Genetics 9, e1003213
Tang, NH; Takada, H; Hsu, K-S and Toda, T (2013)
The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.
Molecular Biology of the Cell 24, 1122-1133
Tang, NH and Toda, T (2013)
Ndc80 Loop as a protein-protein interaction motif.
Cell Division 8, 2
Jourdain, I; Dooley, HC and Toda, T (2012)
Fission yeast Sec3 bridges the exocyst complex to the actin cytoskeleton.
Traffic 13, 1481-1495
Okamoto, S-y; Sato, M; Toda, T and Yamamoto, M (2012)
SCF ensures meiotic chromosome segregation through a resolution of meiotic recombination intermediates.
PLOS ONE 7, e30622
Penney, M; Samejima, I; Wilkinson, CR; McInerny, CJ; Mathiassen, SG; Wallace, M; Toda, T; Hartmann-Petersen, R and Gordon, C (2012)
Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the Pap1 transcription factor.
PLOS ONE 7, e50796
Hsu, K-S and Toda, T (2011)
Ndc80 internal loop interacts with Dis1/TOG to ensure proper kinetochore-spindle attachment in fission yeast.
Current Biology 21, 214-220
Ikebe, C; Konishi, M; Hirata, D; Matsusaka, T and Toda, T (2011)
Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast.
Bioscience, Biotechnology, and Biochemistry 75, 2364-2370
Kume, K; Koyano, T; Kanai, M; Toda, T and Hirata, D (2011)
Calcineurin ensures a link between the DNA replication checkpoint and microtubule-dependent polarized growth.
Nature Cell Biology 13, 234-242
Fong, CS; Sato, M and Toda, T (2010)
Fission yeast Pcp1 links polo kinase-mediated mitotic entry to γ-tubulin-dependent spindle formation.
EMBO Journal 29, 120-130
Goshima, T; Kume, K; Koyano, T; Ohya, Y; Toda, T and Hirata, D (2010)
Fission yeast germinal center (GC) kinase Ppk11 interacts with Pmo25 and plays an auxiliary role in concert with the morphogenesis Orb6 network (MOR) in cell morphogenesis.
Journal of Biological Chemistry 285, 35196-35205
Koyano, T; Kume, K; Konishi, M; Toda, T and Hirata, D (2010)
Search for kinases related to transition of growth polarity in fission yeast.
Bioscience, Biotechnology, and Biochemistry 74, 1129-1133
Sato, M and Toda, T (2010)
Space shuttling in the cell: nucleocytoplasmic transport and microtubule organization during the cell cycle.
Nucleus 1, 231-236
Takayama, Y; Mamnun, YM; Trickey, M; Dhut, S; Masuda, F; Yamano, H; Toda, T and Saitoh, S (2010)
Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function.
Developmental Cell 18, 385-396
Takayama, Y and Toda, T (2010)
Coupling histone homeostasis to centromere integrity via the ubiquitin-proteasome system.
Cell Division 5, 18